Why Trump’s Nominee Is a Victory for Small Business
In my USA Herald Column I write about an important issue. What the SCOTUS nomination of Federal appeals court judge Brett Kavanaugh means for small business. Small business is essential for our country, for the economy, for jobs and for our global competitiveness.
In healthcare, small business, like our team at Advanced Bifurcation System, drives innovations that can improve or lengthen lives.
I hope you will read, share and let me know your comments.
Thank you for reading
Technological Innovations Give Hope in the Fight Against Heart Disease
From apps that diagnose irregular heart rhythms to fitbits with sensors to measure heart rate, a wave of heart technological innovations has appeared as companies cash in on the battle to fight heart disease.
The question always arises of how accurate the results are from a medical point of view. When it comes to measuring blood pressure and more on devices we use every day, like smartphones, there definitely needs to be more research. For example, readings could be influenced by motion, consistent contact with the skin, etc.
Smartphone Blood Pressure Check
Last year Caltech showed that a smartphone app could accurately measure how much blood the hearts pumps with each beat. In turn, all patients had to do was hold a smartphone camera up to their neck for less than two minutes, and an algorithm in the app analyzed the information. This was found to be as accurate as doing an ultrasound.
Other Heart Technological Innovations
Artificial intelligence is changing the way cardiac disease is being handled because of the way data can be absorbed, processed and analyzed. When it comes to healthcare, this can make all the difference in the way patients are diagnosed and treated.
For instance, cardiologists are able to read and interpret the results of echo studies more quickly and efficiently. Catching heart disease early and treating it efficiently is more possible when using AI.
Our dual catheter system is another technological innovation that I hope will bring about a revolution in the way heart disease is treated. Patients will no longer have to undergo lengthy, complex operations. The interventional cardiologist will be able, and the patient will be out the same day.
At present we seem to be losing the fight against heart disease, but technological innovations could make a difference. They have the potential to change cardiac healthcare for the better by addressing current limitations.
The Possibility of Outpatient
One of the most traumatic things a person can go through is open heart surgery. My mission is to help people understand that there could be options.
Heart surgery, among being traumatic, is also very very expensive. My company, Advanced Bifurcation Systems, created a device, that for many, is an outpatient procedure.
Our company has received patents and we have applied for FDA approval. We need to make sure people understand that there could be options. Open Heart surgery may not be needed.
My BioSpace article live and found here.
Asia is a Strategically Important Market for ABS
There have been quite a few exciting new developments at ABS in the last few months. I recently traveled to China to promote our new technology with investors and potential strategic partners. We know that the Asian Market is a great business partnership. The reception was overwhelmingly positive and I look forward to returning in the near future.
Our plans for Asia were recently announced in a press release. In turn, discussed our decision to embark on a new fundraising initiative to raise an additional $20 million.
We believe our stenting technology can reduce the need for open-heart surgery and save many lives. Clinical trials are expensive to conduct though and that’s why we’re targeting these additional funds.
Our Technology is Unique
The way the ABS system works is unique. Our procedure uses a dual catheter system to simultaneously place stents in both the mother and daughter arteries of a bifurcation lesion.
The goal is to simplify a complex procedure and reduce the amount of errors that occur during surgeries. Using current technology, it’s not uncommon for surgeons to have to replace stents within a few months. We want to eliminate that requirement.
Seeing A Need in the Asian Market
Why the focus on China and Asia in general? Unfortunately, this region has experienced a major increase in incidents of cardiac related illness in the last couple of decades. It seems to be getting worse. It’s a market that needs innovative companies like ABS to reverse the trend.
It isn’t just China though. Heart disease is on the rise in other major countries such as India and Japan as well. Part of this is because of greater integration with global markets.
Fast-food chains are quite common in this region of the world now as consumers have more disposable income. They’re also leading more sedentary lives as their affluence is allowing for more leisure time.
While efforts are being made to change lifestyles and improve diets, new and innovative medical procedures must be part of the solution as well.
Our expansion into Asia is an important phase in ABS’s development. We’re excited about the prospects and we’re looking forward to developing new partnerships there. The goal is to make sure we’re ready for production in major Asian markets once final regulatory approval has been achieved.
E-Cigarettes are a very big thing today. My jaw dropped when I read that they have gummy bear and candy flavored ones now. I believe too, that these companies are trying to appeal to young people. Discussions that e-cigarettes are also a gateway form for future cigarette use.
THERE IS NO FORM OF TOBACCO THAT IS GOOD FOR ANYONE. Testing and results have shown the impact of e-cigarettes has upon heart disease.
People think not me, I’m too healthy but they could be destroying their lungs, and increasing the risk of heart attacks. There is no amount of nicotine that can be good for anyone, anytime or anyplace.
Obesity in our Youth
In this article I read, obesity has now become a problem for children in the age bracket of 2 to 5 years of age. This is astounding to me.
This is a real problem with children as there is some much time spent on IPads, cell phones and TV games. In turn, team sports have decreased, playing outdoors has decreased and diets are filed with many foods that add calories.
Parents need to take an active role in making sure their children are healthy. That is a tough statement as all parents care about their children.
However, parents set examples every day with this child. Most parents don’t realize that their children do notice them not eating right and exercising. This vision of their parents has a dramatic effect upon the child. A child’s diet is also so critical. They should be eating fruit instead of donuts, salads and vegetables instead of mac and cheese, etc.
Parental influence can change the obesity problem with children.
Tackling a Global Pandemic
ABS was founded because there’s a real need for improvements in the way we approach the global heart disease problem. Current methods for treating heart disease aren’t always successful. 7.4 million people die from a heart attack every year. Several new technologies could change that and our innovative new stenting platform is one of them. We hope that human clinical trials and FDA review will show that it could reduce the need for open-heart surgery and improve the quality of life for patients suffering from heart disease.
How the ABS System Works
One of the most difficult procedures for heart surgeons is trying to place stents in branched arteries. The ABS system is designed to simplify the process and replace most open-heart surgeries with a less invasive procedure that can be performed as a day surgery.
Open-heart surgery is a stressful experience for the patient and many suffer depression after their operation. A simple day procedure would reduce their anxiety and allow them to return to their daily lives without a significant recovery period.
The method works by using a dual catheter system to place stents in both the mother and daughter vessels of a branched artery at the same time. The technology is self-aligning as well, to reduce the risk of errors and it’s simple to perform. Most cardiac surgeons will be able to perform the procedure without much training.
A Major Part of the Puzzle
The ABS system isn’t the only breakthrough we hope could aid in reducing deaths from heart disease. New technologies in the areas of Artificial Intelligence, apps, and wearable devices are also part of the solution. It’s not difficult to imagine the risk of death from a heart attack being cut in half in the next decade. Technology is allowing people to live longer and healthier lives. I think that Advanced Bifurcation Systems is a major piece of the puzzle along with these other technologies.
Transient Deterioration From Short Term Increase in Heart Fat Content
Research on the health impact of crash diets conducted at the Oxford Centre for Magnetic Resonance at Oxford University found some interesting results. Obese patients on meal replacement diets were 600 to 800 kcal per day for 56 days. While insulin and fat levels did decrease the first week, heart fat levels increased about 44% in the study in the first week. In the first week body fat (of course), visceral fat and liver fat all fell and the patients displayed improvements in insulin resistance, fasting total cholesterol, triglycerides, glucose and blood pressure.
Short Term Stresses On Heart Possible
By the end of the study the heart fat levels had improved beyond where they had started so these diets do display a number of health benefits. Doctors warned that people with heart disease or other cardiovascular conditions should discuss these diets with a health care professional before hand to ensure they can handle the short term impacts.
Dr Rayner said: “The metabolic improvements with a very low calorie diet, such as a reduction in liver fat and reversal of diabetes, would be expected to improve heart function. Instead, heart function got worse in the first week before starting to improve.”
Stress From Environmental Commotion May Be The Cause
Researches have found linkages between environmental sounds, such as those from airplanes and road noise can contribute to the risk factor for heart disease. Research like this is critical since 800 people every minute die of heart disease and that number will go up more than 25% in about 7 years. They linked risk factors including diabetes and hypertension. Turbulent sounds are associated with oxidative stress, vascular dysfunction, autonomic imbalance and metabolic abnormalities.
Thomas Munzel, MD, lead author of the review and director of the Department of Internal Medicine at University Medical Center Mainz, Johannes Cutenberg University, Mainz, Germany, said, “as the percentage of the population exposed to detrimental levels of transportation noise are rising, new developments and legislation to reduce noise are important for public health.”
Today was my third and final day in Shanghai. Tomorrow morning, I leave for Beijing. I am looking forward to seeing the city and am excited at how well the trip has gone.
Most of today I met with some great people from the global company Terumo Corporation.
Terumo is a medical device company with over $4B USD in annual sales. They have lines of business including general hospital devices and supplies such as catheters, thermometers and monitors as well as a business that produces a broad range of blood management devices and supplies. And, of course, they have a cardiac and vascular business as well.
We started out early this morning and covered everything about ABS and our platform. After a few hours we dialed in Doctor Mehran Khorsandi, ABS cofounder and chief medical officer, to cover some questions that were specific to interventional cardiology. Again, after Mehran spoke he answered their questions and left our hosts with no doubt about the ability of cardiologists to transfer to the ABS system. I look forward to follow-up meetings with Terumo at their corporate headquarters in Japan.
This was our second set of meetings with Terumo. We last met with them at the JP Morgan in California a few weeks ago. We also met today with Fosun Pharma and Lilly Asia Ventures. Both meetings were good, and their representatives were well informed on the Asian market. We discussed the regional potential for companies like ABS. Heart disease is a major global problem and kills over 47,000 people a day. So, the hard work by the people at companies like Advanced Bifurcation, Terumo and Fosun Pharma is important to everyone.
Today was a very busy day and the jet lag is catching up with me a bit.